Article
PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor.
Metabolism: clinical and experimental - 1 Apr 2010
Sanghera Dharambir Kaur, Demirci Fatma Yesim, Been Latonya, Ortega Lyda, Ralhan Sarju, Wander Gurpreet Singh, Mehra Narinder Kumar, Singh Jairup, Aston Christopher Eric, Mulvihill John Joseph, Kamboh Ilyas Mohammad
Abstract excerpt
We have examined the association of 14 tagging single nucleotide polymorphisms (tagSNPs) in peroxisome proliferator activated receptor-gamma transcripts 1 and 2 (PPARG1 and 2) and 5 tagSNPs in adiponectin (ADIPOQ) genes for their effect on type 2 diabetes mellitus (T2D) risk in Asian Indian Sikhs. A total of 554 T2D cases and 527 normoglycemic controls were examined for association with T2D and other...
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