Article
Genetic polymorphisms in peroxisome proliferator-activated receptor delta associated with obesity.
Diabetes - 1 Mar 2004
Shin Hyoung Doo, Park Byung Lae, Kim Lyoung Hyo, Jung Hye Seung, Cho Young Min, Moon Min Kyong, Park Young Joo, Lee Hong Kyu, Park Kyong Soo
Abstract excerpt
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors regulating the expression of genes involved in lipid and glucose metabolism. Three different PPARs, PPAR-alpha, -gamma, and -delta, have been characterized, and they are distinguished from each other by tissue distribution and cell activation. All PPARs are, to different extents, activated by fatty acids and derivatives. Recently, it has...
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