Article
PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis.
Scientific reports - 29 Jul 2020
Sarhangi Negar, Sharifi Farshad, Hashemian Leila, Hassani Doabsari Maryam, Heshmatzad Katayoun, Rahbaran Marzieh, Jamaldini Seyed Hamid, Aghaei Meybodi Hamid Reza, Hasanzad Mandana
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a complex disease caused by the interaction between genetic and environmental factors. A growing number of evidence suggests that the peroxisome proliferator-activated receptor gamma (PPARG) gene plays a major role in T2DM development. Meta-analysis of genetic association studies is an efficient tool to gain a better understanding of multifactorial diseases and potentially to...
Topics
- Alleles
- Diabetes Mellitus, Type 2
- Disease Progression
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Odds Ratio
- PPAR gamma