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Article

The anaphase promoting complex contributes to the degradation of the S. cerevisiae telomerase recruitment subunit Est1p.

PloS one - 1 Jan 2013

Ferguson Jenifer L, Chao William Chong Hang, Lee Ethan, Friedman Katherine L

Abstract excerpt

Telomerase is a multi-subunit enzyme that reverse transcribes telomere repeats onto the ends of linear eukaryotic chromosomes and is therefore critical for genome stability. S. cerevisiae telomerase activity is cell-cycle regulated; telomeres are not elongated during G1 phase. Previous work has shown that Est1 protein levels are low during G1 phase, preventing telomerase complex assembly. However, the pathway...

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PMID: 23372810
DOI: 10.1371/journal.pone.0055055
PMCID: PMC3555863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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The anaphase promoting complex contributes to the degradation of the S. cerevisiae telomerase recruitment subunit Est1p.PMID 23372810Read ↗

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