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Article

Role of the ESCRT Complexes in Telomere Biology.

mBio - 8 Nov 2016

Dieckmann Anna K, Babin Vera, Harari Yaniv, Eils Roland, König Rainer, Luke Brian, Kupiec Martin

Abstract excerpt

Eukaryotic chromosomal ends are protected by telomeres from fusion, degradation, and unwanted double-strand break repair events. Therefore, telomeres preserve genome stability and integrity. Telomere length can be maintained by telomerase, which is expressed in most human primary tumors but is not expressed in the majority of somatic cells. Thus, telomerase may be a highly relevant anticancer drug target....

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Share to Endosomal Sorting Complexes Required for Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27834202
DOI: 10.1128/mBio.01793-16
PMCID: PMC5101353

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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