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Article

Modulating membrane composition alters free fatty acid tolerance in Escherichia coli.

PloS one - 1 Jan 2013

Lennen Rebecca M, Pfleger Brian F

Abstract excerpt

Microbial synthesis of free fatty acids (FFA) is a promising strategy for converting renewable sugars to advanced biofuels and oleochemicals. Unfortunately, FFA production negatively impacts membrane integrity and cell viability in Escherichia coli, the dominant host in which FFA production has been studied. These negative effects provide a selective pressure against FFA production that could lead to genetic...

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Identifiers

PMID: 23349781
DOI: 10.1371/journal.pone.0054031
PMCID: PMC3549993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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