Article
Exogenous polyunsaturated fatty acids (PUFAs) promote changes in growth, phospholipid composition, membrane permeability and virulence phenotypes in Escherichia coli.
BMC microbiology - 12 Oct 2020
Herndon Joshua L, Peters Rachel E, Hofer Rachel N, Simmons Timothy B, Symes Steven J, Giles David K
Abstract excerpt
BACKGROUND: The utilization of exogenous fatty acids by Gram-negative bacteria has been linked to many cellular processes, including fatty acid oxidation for metabolic gain, assimilation into membrane phospholipids, and control of phenotypes associated with virulence. The expanded fatty acid handling capabilities have been demonstrated in several bacteria of medical importance; however, a survey of the...
Topics
- Ampicillin
- Anti-Bacterial Agents
- Antimicrobial Cationic Peptides
- Arachidonic Acid
- Biofilms
- Cell Membrane
- Cell Membrane Permeability
- Colistin
- Docosahexaenoic Acids
- Drug Resistance, Bacterial
- Escherichia coli
- Fatty Acids, Unsaturated