Article
Surveying the lipogenesis landscape in Yarrowia lipolytica through understanding the function of a Mga2p regulatory protein mutant.
Metabolic engineering - 1 Sept 2015
Liu Leqian, Markham Kelly, Blazeck John, Zhou Nijia, Leon Dacia, Otoupal Peter, Alper Hal S
Abstract excerpt
Lipogenic organisms represent great starting points for metabolic engineering of oleochemical production. While previous engineering efforts were able to significantly improve lipid production in Yarrowia lipolytica, the lipogenesis landscape, especially with respect to regulatory elements, has not been fully explored. Through a comparative genomics and transcriptomics approach, we identified and validated a...
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