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Article

25-Hydroxy vitamin D3 modulates dendritic cell phenotype and function in Crohn's disease.

Inflammopharmacology - 1 Apr 2013

Bartels Lars E, Jørgensen Søren P, Bendix Mia, Hvas Christian L, Agnholt Jørgen, Agger Ralf, Dahlerup Jens F

Abstract excerpt

BACKGROUND: In Crohn's disease (CrD), vitamin D may help to balance an exaggerated immune response and thereby improve the disease course. The immunomodulating effects depend on the activation of 25-hydroxy vitamin D3 (25-D3), into 1,25-dihydroxy vitamin D3 (1,25-D3). This activation has previously been shown to take place in dendritic cells (DC) from healthy individuals. We hypothesised that DC from CrD patients...

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PMID: 23341164
DOI: 10.1007/s10787-012-0168-y

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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