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Article

1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2009

Széles Lajos, Keresztes Gábor, Töröcsik Dániel, Balajthy Zoltán, Krenács László, Póliska Szilárd, Steinmeyer Andreas, Zuegel Ulrich, Pruenster Monika, Rot Antal, Nagy László

Abstract excerpt

Activation of vitamin D receptor (VDR) by 1,25-dihydroxyvitamin D(3) (1,25-vitD) reprograms dendritic cells (DC) to become tolerogenic. Previous studies suggested that 1,25-vitD could inhibit the changes brought about by differentiation and maturation of DCs. Underpinning the described phenotypic...

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Source

Identifiers

PMID: 19201860
DOI: 10.4049/jimmunol.0803345

Genes

CCL22
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19201860-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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