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Article

Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2011

Von Bubnoff Dagmar, Scheler Marina, Wilms Helene, Fimmers Rolf, Bieber Thomas

Abstract excerpt

Dendritic cells (DCs) can induce tolerance or immunity. We identified and characterized an IDO-expressing and an IDO-negative human DC population after stimulation by various proinflammatory stimuli. IDO expression was strongly dependent on the maturation status of the cells (CD83-positive cells only). The two DC subpopulations remained IDO positive and IDO negative, respectively, over a time period of at least...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21543643
DOI: 10.4049/jimmunol.1003151

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ICOS
TLR3
TLR4

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