Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunomodulatory Effects of 1,25-Dihydroxyvitamin D3 on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens.

Journal of immunology research - 1 Jan 2016

Lee Wai-Ping, Willekens Barbara, Cras Patrick, Goossens Herman, Martínez-Cáceres Eva, Berneman Zwi N, Cools Nathalie

Abstract excerpt

While emerging evidence indicates that dendritic cells (DC) play a central role in the pathogenesis of multiple sclerosis (MS), their modulation with immunoregulatory agents provides prospect as disease-modifying therapy. Our observations reveal that 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) treatment of monocyte-derived DC results in a semimature phenotype and anti-inflammatory cytokine profile as compared to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens
Share to Cryopreservation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Immune Tolerance

Share to Lymphocyte Culture Test, Mixed

Share to Multiple Sclerosis

Share to Myelin Sheath

Share to Vitamin D

Source

Open in PubMed Open full text

Identifiers

PMID: 27703987
DOI: 10.1155/2016/5392623
PMCID: PMC5039280

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunomodulatory Effects of 1,25-Dihydroxyvitamin D3 on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens.PMID 27703987Read ↗

LPS activation is required for migratory activity and antigen presentation by tolerogenic dendritic cells.Semantic proximity Read ↗

Alternatively activated dendritic cells derived from systemic lupus erythematosus patients have tolerogenic phenotype and function.Semantic proximity Read ↗

A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines.Semantic proximity Read ↗

1,25-Dihydroxyvitamin D3 promotes tolerogenic dendritic cells with functional migratory properties in NOD mice.Semantic proximity Read ↗

Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells.Semantic proximity Read ↗

Differential protein pathways in 1,25-dihydroxyvitamin d(3) and dexamethasone modulated tolerogenic human dendritic cells.Semantic proximity Read ↗

1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.Semantic proximity Read ↗

Comparative study of clinical grade human tolerogenic dendritic cells.Semantic proximity Read ↗

Transcriptomic Analysis Identifies A Tolerogenic Dendritic Cell Signature.Semantic proximity Read ↗

Type 1 regulatory T cells and regulatory B cells induced by tolerogenic dendritic cells.Semantic proximity Read ↗

Vitamin D3 targets epidermal and dermal dendritic cells for induction of distinct regulatory T cells.Semantic proximity Read ↗

25-Hydroxy vitamin D3 modulates dendritic cell phenotype and function in Crohn's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.