Article

The immunomodulatory effects of vitamin D in Crohn's disease : dendritic cells, gamma delta T-cells and homing

2012-01-01

Abstract excerpt

Background: Emerging epidemiological evidence implicates Vitamin D insufficiency in the risk of Inflammatory Bowel Disease (IBD). Dendritic cells (DC) are thought to play a pivotal role in the dysregulated intestinal mucosal T-cell mediated immune responses which characterise IBD. In vitro human blood studies and in vivo animal models of IBD, suggest that vitamin D is immunomodulatory inducing a tolerogenic DC phe...

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Literature Corpus work: 4c9dfb38-258c-5361-baf5-434c6c315479
DOI: 10.25560/9904

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