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Article

Analysis of protein-coding mutations in hiPSCs and their possible role during somatic cell reprogramming.

Nature communications - 1 Jan 2013

Ruiz Sergio, Gore Athurva, Li Zhe, Panopoulos Athanasia D, Montserrat Nuria, Fung Ho-Lim, Giorgetti Alessandra, Bilic Josipa, Batchelder Erika M, Zaehres Holm, Schöler Hans R, Zhang Kun, Izpisua Belmonte Juan Carlos

Abstract excerpt

Recent studies indicate that human-induced pluripotent stem cells contain genomic structural variations and point mutations in coding regions. However, these studies have focused on fibroblast-derived human induced pluripotent stem cells, and it is currently unknown whether the use of alternative somatic cell sources with varying reprogramming efficiencies would result in different levels of genetic alterations....

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Identifiers

PMID: 23340422
DOI: 10.1038/ncomms2381
PMCID: PMC3856317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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