Article
Restriction of V3 region sequence divergence in the HIV-1 envelope gene during antiretroviral treatment in a cohort of recent seroconverters.
Retrovirology - 18 Jan 2013
Gall Astrid, Kaye Steve, Hué Stéphane, Bonsall David, Rance Richard, Baillie Gregory J, Fidler Sarah J, Weber Jonathan N, McClure Myra O, Kellam Paul
Abstract excerpt
BACKGROUND: Dynamic changes in Human Immunodeficiency Virus 1 (HIV-1) sequence diversity and divergence are associated with immune control during primary infection and progression to AIDS. Consensus sequencing or single genome amplification sequencing of the HIV-1 envelope (env) gene, in particular the variable (V) regions, is used as a marker for HIV-1 genome diversity, but population diversity is only...
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