Article
Evidence for limited within-person evolution of the V3 domain of the HIV-1 envelope in the amsterdam population.
AIDS (London, England) - 1 Jan 1996
Kuiken C L, Lukashov V V, Baan E, Dekker J, Leunissen J A, Goudsmit J
Abstract excerpt
OBJECTIVE: To study the development of the V3 region of the HIV-1 envelope over time, both within subjects and population-wide. METHODS: Direct V3 sequences were obtained from viral RNA from seroconversion samples of 138 individuals [32 intravenous drug users (IVDU), 106 homosexual men], as well as from 5-year follow-up samples of 45 of these individuals (11 IVDU, 34 homosexual men). RESULTS: The population-wide...
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