Article
HIV-1 genetic diversity and divergence and its correlation with disease progression among antiretroviral naïve recently infected individuals.
Virology - 1 Feb 2020
Leda Ana Rachel, Hunter James, Castro de Oliveira Ursula, Junqueira de Azevedo Inacio, Kallas Esper G, Araripe Sucupira Maria Cecilia, Diaz Ricardo Sobhie
Abstract excerpt
HIV-1 genetic diversity evolution was deeply characterized during the first year of infection among recently-infected patients using deep sequencing technology and correlated with disease progression surrogate markers. RNA and DNA samples from twenty-five individuals (13 female) encoding the protease and reverse transcriptase regions of the pol gene, and the V3 region of the env gene were evaluated at recent...
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