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Article

Effect of antiretroviral therapy on HIV-1 genetic evolution during acute infection.

International journal of STD & AIDS - 1 Mar 2011

Chamberland A, Sylla M, Boulassel M R, Baril J-G, Côté P, Thomas R, Trottier B, Rouleau D, Routy J-P, Tremblay C

Abstract excerpt

The rapid evolution of HIV-1 is a major obstacle to viral eradication. Early antiretroviral therapy (ART) during primary HIV-1 infection could limit viral diversity. Eighteen patients recently infected with HIV-1 were selected. Nine initiated ART soon after enrolment and nine remained untreated. Replication-competent (RC) viruses were quantified at baseline and after one year of follow-up. Viral diversity in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21464451
DOI: 10.1258/ijsa.2010.010292

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