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Article

HIV-1 DNA sequence diversity and evolution during acute subtype C infection.

Nature communications - 21 Jun 2019

Lee Guinevere Q, Reddy Kavidha, Einkauf Kevin B, Gounder Kamini, Chevalier Joshua M, Dong Krista L, Walker Bruce D, Yu Xu G, Ndung'u Thumbi, Lichterfeld Mathias

Abstract excerpt

Little is known about the genotypic make-up of HIV-1 DNA genomes during the earliest stages of HIV-1 infection. Here, we use near-full-length, single genome next-generation sequencing to longitudinally genotype and quantify subtype C HIV-1 DNA in four women identified during acute HIV-1 infection in Durban, South Africa, through twice-weekly screening of high-risk participants. In contrast to chronically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31227699
DOI: 10.1038/s41467-019-10659-2
PMCID: PMC6588551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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