Article
PTCH1 mutation and local aggressiveness of odontogenic keratocystic tumors in children: is there a relationship?
Human pathology - 1 Jun 2013
Kadlub Natacha, Coudert Amélie, Gatibelza Marie-Eve, El Houmami Nawal, Soufir Nadem, Ruhin-Poncet Blandine, L'hermine Aurore Coulomb, Berdal Ariane, Vazquez Marie-Paule, Descroix Vianney, Picard Arnaud
Abstract excerpt
Keratocystic odontogenic tumors (KCOTs) are locally aggressive jaw lesions that may be related to PTCH1 mutations in isolation or in association with nevoid basal cell carcinoma syndrome. We sought to clarify the role of PTCH1 mutation in KCOT aggressiveness. We assessed cyst pathological charact...
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