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Update on the molecular pathology and classification of odontogenic cysts and tumours.

Seminars in diagnostic pathology - 1 Jul 2026

Guimarães Letícia Martins, Odell Edward W, Gomes Carolina Cavalieri

Abstract excerpt

Molecular characterisation of odontogenic cysts and tumours has advanced recently and molecular pathogenesis for several tumour types is included in the 5th edition World Health Organisation (WHO) classification of head and neck tumours. This narrative review examines critically the genetic and signalling alterations reported in odontogenic cysts and tumours and groups them by the signalling pathways affected:...

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Identifiers

PMID: 42361775
DOI: 10.1016/j.semdp.2026.151030

Genes

BRAF
CTNNB1
KRAS
PTCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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