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Article

PTCH1 gene mutations in Keratocystic odontogenic tumors: a study of 43 Chinese patients and a systematic review.

PloS one - 1 Jan 2013

Guo Yan-Yan, Zhang Jian-Yun, Li Xue-Fen, Luo Hai-Yan, Chen Feng, Li Tie-Jun

Abstract excerpt

BACKGROUND: The keratocystic odontogenic tumor (KCOT) is a locally aggressive cystic jaw lesion that occurs sporadically or in association with nevoid basal cell carcinoma syndrome (NBCCS). PTCH1, the gene responsible for NBCCS, may play an important role in sporadic KCOTs. In this study, we analyzed and compared the distribution pattern of PTCH1 mutations in patients with sporadic and NBCCS-associated KCOTs....

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Identifiers

PMID: 24204797
DOI: 10.1371/journal.pone.0077305
PMCID: PMC3804548

Genes

PTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PTCH1 gene mutations in Keratocystic odontogenic tumors: a study of 43 Chinese patients and a systematic review.PMID 24204797Read ↗

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