Article
Analysis of the PTCH1 signaling pathway in ovarian dermoids.
International journal of molecular medicine - 1 Nov 2004
Levanat Sonja, Kappler Roland, Hemmerlein Bernhard, Döring Patrick, Musani Vesna, Komar Arijana, Oreskovic Slavko, Pavelic Bozidar, Hahn Heidi
Abstract excerpt
Dermoids belong to the group of developmental cysts and arise from germ cells. Studies on these tumors may therefore increase our understanding of normal germ cell development within different environments and cell lines derived from these lesions may also constitute an important vehicle for studying neoplasia and differentiation. Recently, we investigated the status of the PTCH1 locus in a large set of sporadic...
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