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Article

PTCH1 and SMO gene alterations in keratocystic odontogenic tumors.

Journal of dental research - 1 Jun 2008

Sun L-S, Li X-F, Li T-J

Abstract excerpt

UNLABELLED: Keratocystic odontogenic tumors (KCOTs, previously known as odontogenic keratocysts) are aggressive jaw lesions that may occur in isolation or in association with nevoid basal cell carcinoma syndrome (NBCCS). Mutations in the PTCH1 (PTCH) gene are responsible for NBCCS and are related in tumors associated with this syndrome. Mutations in the SMO gene have been identified in basal cell carcinoma and in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18502968
DOI: 10.1177/154405910808700616

Genes

PTCH1
SMO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

PTCH1 and SMO gene alterations in keratocystic odontogenic tumors.PMID 18502968Read ↗

PTCH1 gene mutations in Keratocystic odontogenic tumors: a study of 43 Chinese patients and a systematic review.Semantic proximity Read ↗

Biallelic PTCH1 Inactivation Is a Dominant Genomic Change in Sporadic Keratocystic Odontogenic Tumors.Semantic proximity Read ↗

PTCH gene mutations in odontogenic keratocysts.Semantic proximity Read ↗

[PTCH gene mutations in odontogenic keratocysts].Semantic proximity Read ↗

Novel PTCH1 mutations in patients with keratocystic odontogenic tumors screened for nevoid basal cell carcinoma (NBCC) syndrome.Semantic proximity Read ↗

PTCH/SMO gene mutations in odontogenic keratocysts and drug interventions.Semantic proximity Read ↗

[Detection of SMO gene mutations in odontogenic keratocyst].Semantic proximity Read ↗

Identification of known and novel PTCH mutations in both syndromic and non-syndromic keratocystic odontogenic tumors.Semantic proximity Read ↗

Absence of BRAFV600E mutation in odontogenic keratocysts.Semantic proximity Read ↗

[Detection of PTCH gene mutations in odontogenic keratocysts by SSCP and DNA sequencing].Semantic proximity Read ↗

Involvement of PTCH1 mutations in the calcifying epithelial odontogenic tumor.Semantic proximity Read ↗

Molecular alterations in odontogenic keratocysts as potential therapeutic targets.Semantic proximity Read ↗

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