Article
Anti-folate combination therapies and their effect on the development of drug resistance in Plasmodium vivax.
Scientific reports - 1 Jan 2013
Ding Shuai, Ye Run, Zhang Dongmei, Sun Xiaodong, Zhou Hongning, McCutchan Thomas F, Pan Weiqing
Abstract excerpt
Can we predict the rise and spread of resistance to multi-drug therapy in a more predictable manner? We raise this question after analyzing over 500 Plasmodium vivax isolates collected from different, geographically isolated regions of China for sequence variation in and around the dhfr and dhps...
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