Article
The origins and spread of antimalarial drug resistance: lessons for policy makers.
Acta tropica - 1 Jun 2005
Anderson Tim J C, Roper Cally
Abstract excerpt
Understanding the frequency with which new resistance alleles arise and their subsequent patterns of spread is critical to our attempts to manage drug resistance in parasite populations. We review recent molecular evolutionary studies utilizing marker loci situated close to resistance loci on the Plasmodium falciparum genome that have given surprising insights into the origins and spread of drug resistance loci....
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