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Article

A possible genetic link between MTHFR genotype and smoking behavior.

PloS one - 1 Jan 2012

Linnebank Michael, Moskau Susanna, Semmler Alexander, Hoefgen Barbara, Bopp Gisela, Kallweit Ulf, Maier Wolfgang, Schütz Christian G, Wüllner Ullrich

Abstract excerpt

BACKGROUND: Hyperhomocysteinemia is an independent risk factor for stroke and other vascular events. The variant methylenetetrahydrofolate reductase (MTHFR) C677T is associated with elevated homocysteine levels, cardiovascular disease and stroke, which supports a causal relationship between hyper...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homocysteine

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 23285280
DOI: 10.1371/journal.pone.0053322
PMCID: PMC3532068

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23285280-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A possible genetic link between MTHFR genotype and smoking behavior.PMID 23285280Read ↗

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