Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR C677T gene mutation as a risk factor for arterial stroke: a hospital based study.

European journal of neurology - 1 Jan 2005

Alluri R V, Mohan V, Komandur S, Chawda K, Chaudhuri J R, Hasan Qurratulain

Abstract excerpt

Elevated homocysteine level is an independent risk factor for ischemic stroke, thrombotic and cardiovascular diseases. The enzyme methylenetetrahydrofolate reductase (MTHFR) plays a crucial role in regulating the levels of homocysteine. A C677T mutation in this gene results in reduced activity. Sixty-nine patients with arterial stroke, six patients with venous stroke (confirmed by computed tomography and/or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Cytosine
Share to Genetic Carrier Screening

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homocysteine

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Risk Factors

Share to Stroke

Share to Thymine

Source

Identifiers

PMID: 15613145
DOI: 10.1111/j.1468-1331.2004.00938.x

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR C677T gene mutation as a risk factor for arterial stroke: a hospital based study.PMID 15613145Read ↗

C677T and A1298C methylenetetrahydropholate reductase (MTHFR) polymorphisms as factors involved in ischemic stroke.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms are associated with ischemic and hemorrhagic stroke: Dual effect of MTHFR polymorphisms C677T and A1298C.Semantic proximity Read ↗

Acute stroke in relation to homocysteine and methylenetetrahydrofolate reductase gene polymorphismsSemantic proximity Read ↗

Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene (MTHFR gene) with ischemic stroke: a meta-analysis.Semantic proximity Read ↗

Role of MTHFR C677T polymorphism in ischemic stroke.Semantic proximity Read ↗

Relationship between methylenetetrahydrofolate reductase (MTHFR) gene (A1298C) polymorphism with the risk of stroke: A systematic review and meta-analysis.Semantic proximity Read ↗

Association of the methylenetetrahydrofolate reductase gene A1298C polymorphism with stroke risk based on a meta-analysis.Semantic proximity Read ↗

Common genetic variants of homocysteine metabolism in ischemic stroke: a case-control study.Semantic proximity Read ↗

TT genotype of the methylenetetrahydrofolate reductase C677T polymorphism is an important determinant for homocysteine levels in multi-ethnic Malaysian ischaemic stroke patients.Semantic proximity Read ↗

Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China.Semantic proximity Read ↗

[Prevalence of methylenetetrahydrofolate reductase C677T mutation among patients with acute ischemic cerebrovascular disease in Aragon].Semantic proximity Read ↗

ANALYSIS OF RELATIONSHIP BETWEEN POLYMORPHISM OF MTHFR (C677T), MTHFR (A1298C), MTR (A2756G) GENES IN THE DEVELOPMENT OF ISCHEMIC STROKE IN YOUNG PATIENTS.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.