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Article

Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study.

The International journal of neuroscience - 1 Mar 2017

Jiang Shanqun, Li Jianping, Zhang Yan, Venners Scott A, Tang Genfu, Wang Yu, Li Zhiping, Xu Xiping, Wang Binyan, Huo Yong

Abstract excerpt

BACKGROUND: Hyperhomocysteinemia is a risk factor for cardiovascular disease. To date, limited prospective studies have examined the joint effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, hyperhomocysteinemia and conventional vascular risk factors on risk of stroke and stroke death. METHODS: A total of 39 165 subjects from nine communities within Anqing, Anhui Province, China were...

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Identifiers

PMID: 27126505
DOI: 10.1080/00207454.2016.1183126

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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