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Article

Relationship between MTHFR C677T, homocysteine, and ischemic stroke in a large sample of the Han Chinese population.

Medicine - 23 Sept 2022

Jin Ming, Wang Ningning, Li Xueyan, Zhang Hao, Zhou Jexin, Cong Mingyu, Niu Jun, Lin Chongyang, Hu Ying, Wu Nan, Liu Jicheng, Zhang Keyong, Qiu Changchun

Abstract excerpt

Ischemic stroke, one of the prevalent causes of death and disability worldwide, is linked to environmental and genetic factors, including polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene involved in homocysteine metabolism. The present study aimed to explore the relationship between the MTHFR C677T variant, plasma homocysteine, and risk of developing large-artery atherosclerotic ischemic...

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Identifiers

PMID: 36197177
DOI: 10.1097/MD.0000000000030562
PMCID: PMC9509028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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