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Article

Clarifying haplotype ambiguity of NAT2 in multi-national cohorts.

Frontiers in bioscience (Scholar edition) - 1 Jan 2013

Selinski Silvia, Blaszkewicz Meinolf, Agundez Jose A G, Martinez Carmen, Garcia-Martin Elena, Hengstler Jan G, Golka Klaus

Abstract excerpt

N-Acetyltransferase 2 (NAT2) is the key enzyme in aromatic amine metabolism. NAT2 genotyping requires a subsequent determination of the haplotype pairs (formerly: alleles) to derive the acetylation status. The chromosomal phase of the single nucleotide polymorphisms (SNPs) is unclear for about 2/3 of the genotypes. We investigated NAT2 genotypes of 1,234 bladder cancer cases and 2,207 controls from Germany,...

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Source

Identifiers

PMID: 23277078
DOI: 10.2741/s399

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clarifying haplotype ambiguity of NAT2 in multi-national cohorts.PMID 23277078Read ↗

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Global population frequencies of <i>NAT2</i> star alleles observed in three large biobanksSemantic proximity Read ↗

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