Article

Global population frequencies of <i>NAT2</i> star alleles observed in three large biobanks

2026-06-11

Abstract excerpt

NAT2 is an important pharmacogene which encodes the N-acetyltransferase 2 enzyme that is involved in the metabolism of multiple medications, and variants in this gene can affect patient response to these medications. CPIC has published a clinical guideline for prescribing hydralazine using NAT2 genotypes. Just prior to the guideline, updated NAT2 star allele numbering and definitions were released, differing som...

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Literature Corpus work: e0c64354-2b4e-5d03-b664-8a02e730515c
DOI: 10.64898/2026.06.09.26355281

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