Article
A single nucleotide polymorphism tags variation in the arylamine N-acetyltransferase 2 phenotype in populations of European background.
Pharmacogenetics and genomics - 1 Apr 2011
García-Closas Montserrat, Hein David W, Silverman Debra, Malats Núria, Yeager Meredith, Jacobs Kevin, Doll Mark A, Figueroa Jonine D, Baris Dalsu, Schwenn Molly, Kogevinas Manolis, Johnson Alison, Chatterjee Nilanjan, Moore Lee E, Moeller Timothy, Real Francisco X, Chanock Stephen, Rothman Nathaniel
Abstract excerpt
The arylamine N-acetyltransferase 2 (NAT2) slow acetylation phenotype is an established risk factor for urinary bladder cancer. We reported earlier on this risk association using NAT2 phenotypic categories inferred from NAT2 haplotypes based on seven single nucleotide polymorphisms (SNPs) in a st...
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