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Article

Unraveling ambiguous NAT2 genotyping data.

Clinical chemistry - 1 Aug 2008

Agúndez José A G, Golka Klaus, Martínez Carmen, Selinski Silvia, Blaszkewicz Meinolf, García-Martín Elena

Abstract excerpt

BACKGROUND: Arylamine N-acetyltransferase 2 (CoASAc; NAT2, EC 2.3.1.5) is a drug-metabolizing enzyme that displays common polymorphisms leading to impaired drug metabolism and adverse drug effects. Determination of the N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2) genotype in clinical practice is hampered by the occurrence of ambiguous haplotype combinations that may lead to patient...

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Source

Identifiers

PMID: 18664443
DOI: 10.1373/clinchem.2008.105569

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Unraveling ambiguous NAT2 genotyping data.PMID 18664443Read ↗

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Algorithm for the Automated Evaluation of NAT2 Genotypes.Semantic proximity Read ↗

Single nucleotide polymorphism coverage and inference of N-acetyltransferase-2 acetylator phenotypes in wordwide population groups.Semantic proximity Read ↗

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