Article
SWI/SNF gene variants and glioma risk and outcome.
Cancer epidemiology - 1 Apr 2013
Amankwah Ernest K, Thompson Reid C, Nabors L Burton, Olson Jeffrey J, Browning James E, Madden Melissa H, Egan Kathleen M
Abstract excerpt
BACKGROUND: The human SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex plays essential roles in a variety of cellular processes and has been implicated in human cancer. However, the role of germline genetic variants in this complex in relation to cancer risk is not well studied. METHODS: We assessed the association of 16 variants in the catalytic subunits (SMARCA2 and SMARCA4) of the SWI/SNF...
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