Article
Distribution and phenotypic expression of mineralocorticoid receptor and CYP11B2 T-344C polymorphisms in a Taiwanese hypertensive population.
Molecular biology reports - 1 May 2013
Sia Sung-Kien, Chiou Hui-Ling, Chen Shiuan-Chih, Tsai Chin-Feng, Yang Shun-Fa, Ueng Kwo-Chang
Abstract excerpt
Numerous genetic loci are involved in the pathogenesis of hypertension, including genes related to aldosterone synthesis and mineralocorticoid receptor. The aim of this study was to evaluate the genotypic distribution of mineralocorticoid receptor and cytochrome P450 11B2 (CYP11B2) T-344C polymorphisms and their relationship with hypertension and cardiac remodeling in a Taiwanese population. Genomic DNA extracted...
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