Association of aldosterone synthase (CYP11B2 C-344T) gene polymorphism & susceptibility to essential hypertension in a south Indian Tamil population.

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Article

Association of aldosterone synthase (CYP11B2 C-344T) gene polymorphism & susceptibility to essential hypertension in a south Indian Tamil population.

The Indian journal of medical research - 1 Oct 2010

Rajan S, Ramu P, Umamaheswaran G, Adithan C

Abstract excerpt

BACKGROUND & OBJECTIVE: Renin-angiotensin aldosterone system (RAAS) plays an important role in the regulation of blood pressure. Aldosterone, synthesized by aldosterone synthase in the adrenal cortex is encoded by the CYP11B2 gene. In this case-control study we examined the association between CYP11B2 C-344T polymorphism and essential hypertension in south Indian Tamil population. METHODS: The study was conducted...

Topics

Adult
Cytochrome P-450 CYP11B2
DNA Primers
Electrophoresis, Polyacrylamide Gel
Ethnicity
Female
Genetic Predisposition to Disease
Genotype
Humans
Hypertension
India

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Logistic Models

Male

Middle Aged

Odds Ratio

Polymorphism, Single Nucleotide

Renin-Angiotensin System

Source

Open in PubMed

Identifiers

PMID: 20966514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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