Article
Association of the -344T/C aldosterone synthase gene variant with essential hypertension.
Physiological research - 1 Jan 2009
Hlubocká Z, Jáchymová M, Heller S, Umnerová V, Danzig V, Lánská V, Horký K, Linhart A
Abstract excerpt
The aldosterone synthase gene (CYP11B2) is an important candidate gene region in essential hypertension. We therefore studied the association of -344T/C polymorphism of the CYP11B2 gene with the presence and severity of hypertension in a case-control study. We studied 369 individuals, of whom 213 were hypertensive patients (139 controlled hypertensive, 74 resistant hypertensive) and 156 were healthy normotensive...
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