Association of BRCA1 promoter methylation with rs11655505 (c.2265C>T) variants and decreased gene expression in sporadic breast cancer.

doi:10.1007/s12094-012-0968-y

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of BRCA1 promoter methylation with rs11655505 (c.2265C>T) variants and decreased gene expression in sporadic breast cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Jul 2013

Hasan Tarique N, Leena Grace B, Shafi Gowhar, Syed Rabbani

Abstract excerpt

OBJECTIVE: Breast cancer is the most common cancer and the main cause of cancer morbidity for women worldwide and is manifestation of abnormal genetic as well as epigenetic changes. Therefore, our aim was to study the association of BRCA1 promoter methylation with rs11655505 (c.-2265C/T) variants and gene expression in sporadic breast cancer. METHODS: Twenty-nine sporadic breast cancer tissues and 26 normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

Share to Gene Silencing

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 23263908
DOI: 10.1007/s12094-012-0968-y

Genes

BRCA1

Variants

rs11655505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of BRCA1 promoter methylation with rs11655505 (c.2265C>T) variants and decreased gene expression in sporadic breast cancer.PMID 23263908Read ↗

A BRCA1 promoter variant (rs11655505) and breast cancer risk.Semantic proximity Read ↗

Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology.Semantic proximity Read ↗

Association of the BRCA1 promoter polymorphism rs11655505 with the risk of familial breast and/or ovarian cancer.Semantic proximity Read ↗

BRCA1-methylated sporadic breast cancers are BRCA-like in showing a basal phenotype and absence of ER expression.Semantic proximity Read ↗

Epigenetic silencing and deletion of the BRCA1 gene in sporadic breast cancer.Semantic proximity Read ↗

BRCA1 promoter methylation is a marker of better response to anthracycline-based therapy in sporadic TNBC.Semantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood DNA was identified in sporadic breast cancer and controls.Semantic proximity Read ↗

Wild-type genotypes of BRCA1 gene SNPs combined with micro-RNA over-expression in mammary tissue leading to familial breast cancer with an increased risk of distant metastases' occurrence.Semantic proximity Read ↗

Peripheral blood DNA methylation detected in the BRCA1 or BRCA2 promoter for sporadic ovarian cancer patients and controls.Semantic proximity Read ↗

MYC overexpression and poor prognosis in sporadic breast cancer with BRCA1 deficiency.Semantic proximity Read ↗

Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.