Article
Investigation of DNA damage response and apoptotic gene methylation pattern in sporadic breast tumors using high throughput quantitative DNA methylation analysis technology.
Molecular cancer - 23 Nov 2010
Pal Ranjana, Srivastava Niloo, Chopra Rupali, Gochhait Sailesh, Gupta Pawan, Prakash Neeraj, Agarwal Gaurav, Bamezai Rameshwar N K
Abstract excerpt
BACKGROUND: Sporadic breast cancer like many other cancers is proposed to be a manifestation of abnormal genetic and epigenetic changes. For the past decade our laboratory has identified genes involved in DNA damage response (DDR), apoptosis and immunosurveillance pathways to influence sporadic breast cancer risk in north Indian population. Further to enhance our knowledge at the epigenetic level, we performed...
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