Association of the BRCA1 promoter polymorphism rs11655505 with the risk of familial breast and/or ovarian cancer.

doi:10.1007/s10689-013-9647-6

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Association of the BRCA1 promoter polymorphism rs11655505 with the risk of familial breast and/or ovarian cancer.

Familial cancer - 1 Dec 2013

Bielinska Beata, Gaj Pawel, Kluska Anna, Nowakowska Dorota, Balabas Aneta, Dabrowska Michalina, Niwinska Anna, Gruchota Jakub, Zub Renata, Skasko Elzbieta, Steffen Jan, Ostrowski Jerzy, Siedlecki Janusz A

Abstract excerpt

Germline mutations in the BRCA1 tumor suppressor gene predispose affected individuals to breast cancer; however, incomplete cancer penetrance and the presence of phenocopies in BRCA1 families also indicate genetic and environmental modifiers of breast cancer risk. In this study, we have tested the single nucleotide polymorphism rs1655505 of the BRCA1 promoter, as candidate for the modifier of breast cancer risk....

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PMID: 23657760
DOI: 10.1007/s10689-013-9647-6

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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