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Article

Peripheral blood DNA methylation detected in the BRCA1 or BRCA2 promoter for sporadic ovarian cancer patients and controls.

Clinica chimica acta; international journal of clinical chemistry - 15 Jul 2011

Bosviel Rémy, Michard Emilie, Lavediaux Guillaume, Kwiatkowski Fabrice, Bignon Yves-Jean, Bernard-Gallon Dominique J

Abstract excerpt

BACKGROUND: Ovarian cancer is located at the fifth rank of female cancers. Different risk factors including genetic factors with BRCA1 and BRCA2 genes played an important role in the etiology of the ovarian cancer. In most of sporadic ovarian cancer, variation in the expression of BRCA1 and BRCA2 genes was observed and it could be a consequence of epigenetic modifications. This work aimed to study methylation at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukocytes, Mononuclear

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 21557934
DOI: 10.1016/j.cca.2011.04.027

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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