Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women.

International journal of oncology - 1 Jul 2011

Al-Moghrabi Nisreen, Al-Qasem Abeer J S, Aboussekhra Abdelilah

Abstract excerpt

Early-onset breast cancer is one of the most common malignancies and causes of death among young women, and its incidence is increasing. In the present study, we aimed to investigate the epigenetic modifications of the breast cancer type 1 susceptibility gene (BRCA1) in breast tissues and blood cells derived from women with breast cancer and women without breast cancer. BRCA1 promoter methylation was examined by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Blood Cells
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CpG Islands

Share to Cytosine

Share to DNA Methylation

Share to Epigenomics

Share to Gene Order

Source

Identifiers

PMID: 21537840
DOI: 10.3892/ijo.2011.1021

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women.PMID 21537840Read ↗

Constitutional methylation of the BRCA1 promoter is specifically associated with BRCA1 mutation-associated pathology in early-onset breast cancer.Semantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood cells is associated with increased risk of breast cancer with BRCA1 promoter methylation.Semantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood DNA was identified in sporadic breast cancer and controls.Semantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood is associated with the risk of triple‐negative breast cancerSemantic proximity Read ↗

Methylation profiles of the BRCA1 promoter in hereditary and sporadic breast cancer among Han Chinese.Semantic proximity Read ↗

CLINICAL SIGNIFICANCE OF BRCA1 GENE SEQUENCING AND ITS PROMOTER METHYLATION TESTING IN THE SEARCH STRATEGY FOR THERAPEUTIC TARGETS IN BREAST CANCER TREATMENT.Semantic proximity Read ↗

BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype.Semantic proximity Read ↗

Epigenetic changes in BRCA1-mutated familial breast cancer.Semantic proximity Read ↗

BRCA1 deficiency is a recurrent event in early-onset triple-negative breast cancer: a comprehensive analysis of germline mutations and somatic promoter methylationSemantic proximity Read ↗

Hypermethylation of Tumor Suppressor Genes Involved in Critical Regulatory Pathways for Developing a Blood-Based Test in Breast CancerSemantic proximity Read ↗

Constitutive promoter methylation of BRCA1 and RAD51C in patients with familial ovarian cancer and early-onset sporadic breast cancer.Semantic proximity Read ↗

Peripheral blood DNA methylation analysis reveals epigenetic marks associated with hereditary breast and ovarian cancer riskSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.