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Article

MYC overexpression and poor prognosis in sporadic breast cancer with BRCA1 deficiency.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2013

Ren Jie, Jin Feng, Yu Zhaojin, Zhao Lin, Wang Lin, Bai Xuefeng, Zhao Haishan, Yao Weifan, Mi Xiaoyi, Wang Enhua, Olopade Olufunmilayo I, Wei Minjie

Abstract excerpt

Breast cancer is a complex disease; the molecular mechanisms involved in sporadic breast carcinogenesis remain to be elucidated. The present study aimed to explore the deficiency of breast cancer susceptibility gene 1 (BRCA1), including protein loss expression, promoter hypermethylation and gene copy deletion, its correlationship with other tumor markers expression (TP53, MYC, etc.), and clinical significance in...

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Source

Identifiers

PMID: 23860775
DOI: 10.1007/s13277-013-0983-9

Genes

BRCA1
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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