Article
A factor binding GATAAG confers tissue specificity on the promoter of the human zeta-globin gene.
Nucleic acids research - 25 Mar 1990
Watt P, Lamb P, Squire L, Proudfoot N
Abstract excerpt
We describe the characterisation of cis-acting sequences which control the tissue specific expression of the human zeta globin gene. An extensive search for enhancer sequences in the vicinity of this gene proved negative. Instead our data demonstrate that the minimal promoter of the zeta gene is itself tissue specific. Sequences close to and possibly including the -100 CACCC and -70 CCAAT boxes display some...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.