Article
The upstream region of the human gamma-globin gene promoter. Identification and functional analysis of nuclear protein binding sites.
The Journal of biological chemistry - 25 Jun 1991
McDonagh K T, Lin H J, Lowrey C H, Bodine D M, Nienhuis A W
Abstract excerpt
The promoter of the human gamma-globin gene confers tissue specificity as well as developmental stage specificity to gamma gene expression. Earlier work in our laboratory suggested that a fragment of the gamma-globin promoter between -300 and -137 base pairs upstream of the transcription start site contributed to the developmental specificity of the promoter. In this paper, we have mapped potential regulatory...
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