Article
Protein-DNA interactions upstream from the human A gamma globin gene.
Nucleic acids research - 25 Apr 1990
O'Neill D, Kaysen J, Donovan-Peluso M, Castle M, Bank A
Abstract excerpt
We have used DNAase I footprinting and the gel mobility shift assay to study proteins which bind to promoter elements located between -140 and -382 upstream of the human A gamma globin gene. Footprints are found with both erythroid and nonerythroid nuclear extracts at three sites: from -294 to -264, -242 to -227, and -189 to -172 from the transcription initiation site. An erythroid-specific footprint is...
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