Article
Testicular GATA-1 factor up-regulates the promoter activity of rat inhibin alpha-subunit gene in MA-10 Leydig tumor cells.
Molecular endocrinology (Baltimore, Md.) - 1 Mar 1998
Feng Z M, Wu A Z, Chen C L
Abstract excerpt
We have previously demonstrated that the basal transcription of rat inhibin alpha-subunit gene in a mouse testicular Leydig tumor cell line, MA-10, depends upon a 67-bp DNA fragment at the position of -163 to -97. Within this promoter region two GATA motifs were observed. In this study, we investigated the possible role of GATA-binding proteins in the regulation of inhibin alpha-subunit gene transcription in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
