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Article

Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene.

The Journal of biological chemistry - 31 Dec 2004

Wong Ellice Y, Lin Jolinta, Forget Bernard G, Bodine David M, Gallagher Patrick G

Abstract excerpt

Alpha-spectrin is a membrane protein critical for the flexibility and stability of the erythrocyte. We are attempting to identify and characterize the molecular mechanisms controlling the erythroid-specific expression of the alpha-spectrin gene. Previously, we demonstrated that the core promoter of the human alpha-spectrin gene directed low levels of erythroid-specific expression only in the early stages of...

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PMID: 15456760
DOI: 10.1074/jbc.M408886200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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