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Article

Familial atypical hemolytic uremic syndrome: a review of its genetic and clinical aspects.

Clinical & developmental immunology - 1 Jan 2012

Bu Fengxiao, Borsa Nicolo, Gianluigi Ardissino, Smith Richard J H

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a rare renal disease (two per one million in the USA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Both sporadic (80% of cases) and familial (20% of cases) forms are recognized. The study of familial aHUS has implicated genetic variation in multiple genes in the complement system in disease pathogenesis, helping to...

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Identifiers

PMID: 23251215
DOI: 10.1155/2012/370426
PMCID: PMC3509654

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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